Category: PicoProbe

Phylogenic analysis of coronavirus genome and molecular studies on potential anti-COVID-19 agents from selected FDA-approved drugs

The emergence of 2019 novel Coronavirus (COVID-19 or 2019-nCoV) has induced vital international morbidity and mortality with no consensus particular therapy. We examined the speculation that FDA-approved antiretrovirals, antibiotics, and antimalarials will successfully inhibit COVID-19 two main drug targets, coronavirus nucleocapsid...

Identification of Core Genes and Screening of Potential Targets in Glioblastoma Multiforme by Integrated Bioinformatic Analysis

Glioblastoma multiforme is the most typical main intracranial malignancy, however its etiology and pathogenesis are nonetheless unclear. With the deepening of human genome analysis, the analysis of glioma subtype screening primarily based on core molecules has turn out to be extra...

Genetic predisposition to long telomeres is associated with increased mortality after melanoma: a study of 2101 melanoma patients from hospital clinics and the general population

Whether or not there’s an affiliation between measured and genetically predicted telomere size and melanoma mortality is unclear. We examined the hypotheses that measured and genetically predicted telomere size are related to mortality after a melanoma analysis. We adopted 2101sufferers with...

Screening and bioinformatical analysis of differentially expressed genes in nasopharyngeal carcinoma

To determine differentially expressed genes by way of bioinformatical evaluation for nasopharyngeal carcinoma (NPC) and discover potential biomarkers for NPC. We downloaded the NPC gene expression datasets (GSE40290, GSE53819) and obtained differentially expressed genes (DEGs) by way of GEO2R. Useful evaluation...

Hepatic expression of cholesterol regulating genes favour increased circulating low-density lipoprotein in HIV infected patients with gallstone disease: a preliminary study

HIV endemic populations are displaying larger incidence of metabolic issues. HIV and the usual therapy are each related to altered lipid and ldl cholesterol metabolism, nevertheless gallstone illness (a ldl cholesterol associated dysfunction) in Sub-Saharan African populations isn’t investigated. This research sought...

Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments

Gene-environment interactions (GxE) are sometimes urged to play an necessary position within the aetiology of psychiatric phenotypes, but to this point, solely a handful of genome-wide atmosphere interplay research (GWEIS) of psychiatric phenotypes have been carried out. Representing essentially the most...